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Feng, Xie M.D.

University of Nebrasca Medical Center
Omaha, NE 68198
(402) 559-8890(Office)
Not available

Affiliation with

Lifetime member

Vise President (2014-2015)

CNAHA Committees and Chairs (2014-2015)

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Dr. Feng Xie was born in Nanjing, China in 1954. He graduated from the Jiamusi Medical School in 1975.  His cardiology training took place at the Chinese PLA Postgraduate Medical School during 1982 – 1985. He went to the University of Rochester Medical Center for an advanced postdoctoral training from 1986 – 1987.  He became an associate professor and vice director in the Department of Diagnostic Ultrasound at the Chinese PLA General Hospital in 1990.  In 1992, he was a visiting professor at the University of Pennsylvania Medical Center. He worked at University of Nebraska Medical Center as a research associate and instructor from 1993-1995.  In 1996, he was appointed as a Chief of Department of Ultrasound at Chinese Cardiovascular Institute and Fuwai Heart Hospital, Peking Union Medical College and Chinese Medical Academy.  He is currently an associate professor of medicine at the University of Nebraska Medical Center.

He is a member of American Heart Association and American Society of Echocardiography. He served for American Journal of Cardiology, Journal of American Society of Echocardiography and American Heart Journal as a reviewer. Dr. Xie’s research interests are cardiac imaging and therapeutic ultrasound with microbubbles in coronary heart diseases. He is working several projects as the principal investigator funded by NIH.  He has published more than 100 articles in Circulation, Journal of American College of Cardiology, European Heart Journal etc. He holds several United States Patents and numerous professional awards in his medical career.  

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谢峰是美国心脏学会会员、美国超声心动图学会会员、美国华裔心脏协会副主席,同时也是美国超声心动图学会国际关系中国事务负责人,主持多项ASE指南的中文翻译。他还是若干美国专业杂志的审稿人。谢峰的研究兴趣是心脏影像学和超声与微泡的治疗学领域。他目前作为PI或共同研究者,正在进行几个NIH项目的研究。他已在同行评审的杂志上发表了100篇以上原始工作论文,这些杂志包括:Circulation, Journal of American College of Cardiology, European Heart Journal 等。

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Selected publication

1. Xie F, Tsutsui JM, McGrain AC, Demaria A, Cotter B, Becher H, Lebleu C, Labovitz A, Picard MH, O’leary EL, Porter TR. Comparison of dobutamine stress echocardiography with and without real-time perfusion imaging for detection of coronary artery disease. Am J Cardiol 2005;96:506-11

2. Xie F, Tsutsui JM, Lof J, Unger EC, Johanning J, Culp WC, Matsunaga T, Porter TR.  Effectiveness of Lipid Microbubbles and Ultrasound in Declotting Thrombosis.  Ultrasound Med Biol 2005;31:979-85.

3. Xie F, Tsutsui JM, Gao L, Zucker IH, Porter TR. Interactions of Transthoracic Ultrasound and Intravenous Microbubbles with Cardiac Mechanoreceptors. Ultrasound in Med & Bio 2007;33:136-144

4. Xie F, Hankins J, Mahrous H, Porter TR. Detection of Coronary Artery Disease with a Continuous Infusion of Definity Ultrasound Contrast during Adenosine Stress Real Time Perfusion Echocardiography. Echocardiography 2007; 24:1044-50

5. Xie F, Dodla S, O’Leary E, Porter TR.  Detection of Subendocardial Ischemia in the Left Anterior Descending Coronary Artery Territory With Real-Time Myocardial Contrast Echocardiography During Dobutamine Stress Echocardiography. J Am Coll Cardiol Img 2008;1:271–8

6. Xie F,  Boska M, Lof J, Uberti MG, Tsutsui JM, Porter TR.  Effects of Transcranial Ultrasound and Intravenous Microbubbles on Blood Brain Barrier Permeability in a Large Animal Model. Ultrasound Med Biol 2008;34:2028-34

7. Xie F, Lof J, Matsunaga T, Zutshi R, Porter TR. Diagnostic Ultrasound Combined With Glycoprotein IIb/IIIa-Targeted Microbubbles Improves Microvascular Recovery After Acute Coronary Thrombotic Occlusions. Circulation. 2009;119:1378-1385

8. Xie F, Lof J, Everbach C, He A, Bennett RM, Matsunaga T, Johanning J, Porter TR. Treatment of acute intravascular thrombi with diagnostic ultrasound and intravenous microbubbles. JACC Cardiovasc Imaging. 2009 2:511-8.

9. Xie F, Everbach EC, Gao S, Brvol LK, Shi WT, Vignon F, Powers JE, Lof J, Porter TR.  Effects of attenuation and thrombus age on the success of ultrasound and microbubble-mediated thrombus dissolution.  Ultrasound Med Biol 2011;37:280-8

10. Xie F, Slikkerverr J, Gao S, Lof J, Kamp O, Unger E, Radio S, Matsunaga T, Porter TR.  Coronary and microvascular thrombolysis with guided diagnostic ultrasound and microbubbles in acute ST segment elevation myocardial infarction.  J Am Soc Echocardiogr 2011;24:1400-8

11. Vignon F, Shi WT, Powers J, Liu J, Drol L, Lof J, Everback C, Gao S, Xie F, Porter TP. Real-time two-dimensional imaging of microbubble cavitation. AIP Conference Proceedings. 1481:407-413.2012.

12. Thomas D, Xie F, Smith LM, O’Leary E, Smith K, Olson J, Nalty K, Hess R, Graham M, Therrien S, Porter TR. Prospective randomized comparison of conventional stress echocardiography and real-time perfusion stress echocardiography in detecting significant coronary artery disease. J Am Soc Echocardiogr. 2012 Nov;25(11):1207-14.

13. Porter TR, Xie F. Can transcranial ultrasound and microbubble thrapy ever enter the mainstream in acute stroke therapy?  Expert Rev Cardiovasc Ther.2012 MayP;10(5):549-51.

14. Kutty S. Olson J, Danford CJ, Sandene EK, Xie F, Fletcer SE, Erickson CC, Kugler JD, Danford DA, Porter TR. Ultrasound contrast and real-time perfusion in conjunction with spine bicycle stress echocardiography for comprehensive evaluation of surgically corrected congenital heart disease.  Eur Heart J Cardiovasc Imaging. 2012 Jun;13(6):500-9.

15. Kutty S, Wu J, Hammel JM, Xie F, Gao S, Drvol LK, Lof J, Radio SJ, Therrien SL, Danford DA, Porter TR. Microbubble mediated thrombus dissolution with diagnostic ultrasound for the treatment of chronic venous thrombi.  PLos One 2012;7(12)e51453

16. Liu Z, Gao S, Zhao Y, Li, P, Liu, J, Li, P, Tan, K, Xie F. Disruption of tumor neovasculature by microbubble enhanced ultrasound: A potential new physical therapy of anti-angiogenesis. Ultrasound Med Biol.2012 Feb;38(2):253-61.

17. Liu J, Gao S, Porter T, Everbach C, Shi W, Vignon F, Powers J, Lof J, Turner J, Xie F. Transcranial threshold of inertial cavitation induced by diagnostic ultrasound and microbubbles.  AIP Conference Proceedings 2012; 1481:221-226

18. Porter TR, Smith LM, Wu J, Thomas D, Hass JT, Mathers DH, Williams E, Olson J, Nalty K, Hess R, Therrien S, Xie F. Patient Outcome Following 2 Different Stress Imaging Approaches: A Prospective Randomized Comparison. J Am Coll Cardiol 2013;61(24)2446-2455.

19. Xie F, Gao S, Wu J, Lof J, Radio SJ, Vignon F, Shi W, Powers J, Unger E, Everbach EC, Liu J, Porter, TR. Diagnostic Ultrasound Induced Inertial Cavitation to Non-invasively Restore Coronary and Microvascular Flow in Acute Myocardial Infarction 2013 Plos One 8(7): e69780

20. Vignon F, Shi WT, Powers JE, Everbach EC, Liu J, Gao S, Xie F, Porter TR. Microbubble cavitation imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Apr;60(4):661-70.

21. Gao S, Liu Z, Xie F. Reply to the Letter to the Editor re “Disruptions of Tumor Neovasculature by Microbubble Enhanced Ultrasound: A Potential New Physical Therapy of Anti-angiogenesis”. Ultrasound in Medicine and Biology. 440-456.2014

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