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Jie, Cheng M.D.

Texas Heart Institute
6770 Bertner Avenue MC2-255
Houston, TX 77030
Not available

Affiliation with
Lifetime member
Chair, Academic Affairs 2009-2011
Vice Chairman, Board of Trustees 2012-

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Dr. Jie Cheng graduated from the Shanghai Second Medical University in Shanghai China in 1982 and went on to earn a Master of Science and Doctor of Philosophy at the Case Western Reserve University (CWRU) in Cleveland Ohio where he majored in Biomedical Engineering between 1983 and 1988. His dissertation project was on the mathematical modelling of atrioventricular conduction. After completion of his formal education, Dr. Cheng spent 3 years in basic science research as a recipient of an Individual Research Service Award from the National Institute of Health before he began clinical residency training in Internal Medicine (1991-1994 at the Mt. Sinai Medical Center in Cleveland), fellowship in Cardiology (1994-1996 at the University of Chicago) and fellowship in Cardiac Eletrophysiology (1996-1998 at the University of California San Francisco). Currently he serves as the Director of the Cardiac Electrophysiology Research Laboratory at the Texas Heart Institute and Clinical Associate Professor at the Baylor college of Medicine.

His major research interests are innovative therapy for complex cardiac arrhythmias and basic understanding of the mechanisms underlying these arrhythmias. His contribution to the field of cardiac arrhythmias has been well recognized internationally. In recent years, his basic science research laboratory has focused its effort on the molecular and cellular mechanisms by which the neuronally released polypeptides act on the electrophysiological properties of the heart.
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程杰, 医学博士

程杰博士于1982年毕业中国上海第二医科大学,随后于1983至1988年间,在位于俄亥俄州克利夫兰的凯斯西储大学攻读生物医学科学硕士学位和博士学位。他的博士课题是研究基于数学模型的房室传导。此后,在他开始临床住院医师培训之前,他在美国国家研究院的“国家个人研究服务奖”基金的支助下,开展了为期三年的基础研究。他分别在完成了内科住院医师(1991-1994年 在克里夫兰西奈山医疗中心),心血管内科专科医师(1994-1996 在芝加哥大学),心脏电生理专科医师(1996-1998加利福尼亚大学 旧金山分校)的培训。目前任职于贝勒医学院临床副教授,德州心脏中心心脏电生理研究室主任。

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Selected publication

List of 10 major publications

1. Yang T, Cheng J, and Levy MN: Effects of spatial dispersion of acetylcholine release on the chronotropic responses to vagal stimulation in dogs.  Circ. Res. 67:844-851, 1990. PMID: 2208610
2. Cheng J, and Scheinman MM: Charateristics of double-wave reentry induced by programmed stimulation in patients with typical atrial flutter. Circulation 97:1589-1596, 1998. PMID: 9593564
3. Cheng J, Cabeen WR Jr, and Scheinman MM: Right atrial flutter due to lower-loop reentry: mechanism and anatomic substrate. Circulation 99:1700-1705, 1999. PMID: 10190879
4. Glatter KA, Cheng J, Dorostkar PC, Modin G, Talwar S, Al-Nimri M, Lee RJ, Saxon LA, Lesh MD, Scheinman MM: Electrophysiologic effects of adenosine in patients with supraventricular tachycardia. Circulation 99:1034-1040, 1999. PMID: 10051297
5. Yang Y, Cheng J, Bochoeyer A, Hamdan MH, Kowal RC, Page R, Lee RJ, Steiner PR, Saxon LA, Lesh MD, Modin GW, Scheinman MM: Atypical right atrial flutter patterns. Circulation, 103(25):3092-3098, 2001. PMID: 11425774
6. Cheng J, Glatter KA, Yang YF, Zhang S, Lee RJ and Scheinman MM: Electrophysiological Response of the Right Atrium to Ibutilide During Typical Atrial Flutter. Circulation 106:814-819, 2002. PMID: 12176953
7. Zhang SL, Younis G, Gao LJ, Yang Y, Ip J, Thakur RK, Scheinman MM, Cheng J: Lower loop reentry as a mechanism of clockwise right atrial flutter. Circulation 6;109(13):1630-5, 2004. PMID: 15037534
8. Cheng J, Yang Y, Ursell PC, Lee RJ, Dorostkar PC, Boahene KA, Scheinman: Protected circumferential conduction in the posterior atrioventricular vestibule of the left atrium: electrophysiologic and anatomic correlates. Pacing Clin Electrophysiol. Jul;28(7):692-701, 2005. PMID: 16008806 
9. Shuraih M, Ai T, Vatta M, Sohma Y, Merkle EM, Taylor E, Li Z, Razavi M, Towbin JA, Cheng J: A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents. J Cardiovasc Electrophysiol. 2007;18(4):434-40. PMID: 17331104
10. Yang DH, Xi Y, Ai T, Wu G, Sun JP, Razavi M, Delapasse S, Shurail M, Gao L, Mathuria N, Elayda M and Cheng J: Vagal stimulation promotes atrial electrical remodeling induced by rapid atrial pacing in dogs: evidence of a noncholinergic effect. Pacing Clin Electrophysiol. 2011; 34(9):1092–1099.  PMID: 21793861
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