Biography Hong Wang, MD. PhD. EMBA. FAHAProfessor of Pharmacology Assisten Dean for Reseach Temple University School of Medicine MRB, rm 307, 3420 N Broad Street, Philadelphia, PA, 19140 Phone: 215-707-5986 Fax: 215-707-7068 Email: hongw@temple.edu Affiliation with www.CNAHA.org Lifetime member Chair, Academic Affairs (2012-2013) Affiliation with www.theACRE.org Lifetime member Chair, Education and Award Committee (2011-present) Dr. Hong Wang received her medical training from JinagXi Medical School, an MS degree from Peking Union Medical University, a PhD degree in Biochemistry from University of Montreal, and an EMBA degree from Fox Business School in Temple University. She did her post-doctoral fellowship and then was a research associate in Harvard School of Public Health from 1996 to 1999. She joined faculty in Baylor College of Medicine as an assistant professor in 1999. She moved to Temple University School of Medicine as an associate professor in 2005, and became a tenured professor in 2007. Dr. Wang currently is a pharmacology professor and Assistant Dean for Research at Temple University School of Medicine (TUSM). She teaches Pharmacology in TUSM, Podiatry School of Medicine, School of Dentistry and Temple University Graduate School. Her research focuses are cardiovascular inflammation, atherosclerosis, vascular function, molecular mechanism, and signal transduction. She is an editorial member of JCI, Circulation, J Molecular & Cellular Cardiology and Clinical Medicine: Pathology. 王虹，医学博士、哲学博士 高层管理人员工商管理硕士、美国心脏学会研究员 坦普尔大学医学院药理学教授、科研副院长 王虹博士毕业于江西医学院， 后获得北京协和医科大学理学硕士、蒙特利尔大学生物化学博士、和坦普尔大学Fox商学院高层工商管理硕士。她于1996-1999年在哈佛公共卫生学院从事博士后研究并成为助理研究员；1999年加盟贝勒医学院成为助理教授，2005年转到坦普尔大学医学院成为副教授, 2007成为终身教授。 目前，王博士在坦普尔大学医学院(TUSM)担任药理学教授、TUSM科研副院长，并在TUSM、坦普尔脚足病学院、口腔学院, 研究生院教授药理学和分子生物学课程。其研究方向为心血管炎症、动脉粥样硬化、血管功能、分子机制和信号转导；并担任JCI、Circulation和J Molecular & Cellular Cardiology and Clinical Medicine: Pathology的编委。 Selected Publications of Importance to the Field Wang H‡, Jiang XH, Yang F, Gaubatz JW, Ma L, Magera MJ, Yang XF, Berger PB, Durante W, Pownall HJ, Schafer AI, Hyperhomocysteinemia accelerates atherosclerosis in cystathionine β-synthase and apolipoprotein E double knockout mice with and without dietary perturbation, Blood 2004;101:3901-3907, ‡ Corresponding author, PMID: 12506016 Jiang XH, Yang F, Tan HM, Liao D, Bryan RM Jr., Durante W, Rumbaut RE, Yang XF, Wang H, Hyperhomocysteinemia impairs endothelial function and eNOS activity via protein kinase C activation, Arterioscler Thromb Vasc Biol 2005;25:2515-2521, PMID: 16226235 Tan HM, Jiang XH, Yang F, Li ZH, Liao D, Trial J, Magera M, Durante W, Yang XF, Wang H, Hyperhomocysteinemia inhibits post injury re-endothelialization in mice, Cardiovascular Res 2006;69:253-262, PMID: 16226235 Liao D, Tan HM, Hui RT, Li ZH, Jiang XH, Yang F, Gaubatz JW, Durante W, Chan L, Schafer AI, Pownall HJ, Yang XF, Wang H. Hyperhomocysteinemia Decreases Circulating High-Density Lipoprotein by Inhibiting Apolipoprotein A-I Protein Synthesis and Enhancing HDL Cholesterol Clearance. Circ. Res 2006;99:598-606, PMID: 16931800 [Accompanied by an Editorial: Circ. Res. 99:565-566] Jiang XH, Yang F, Brailoiu E, Jakubowski H, Dun NJ, Schafer AI, Yang XF, Durante W and Wang H, Differential regulation of homocysteine transport in vascular endothelial and smooth muscle cells, Arterioscler. Thromb. Vasc. Biol 2007;27:1976-83, PMID: 17715404 Jamaluddin SM, Chen I, Yang F, Jiang XH, Jan M, Liu XM, Schafer AI, Durante W, Yang XF, and Wang H, Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood 2007;110:3648-3655, PMID: 17698632 [Accompanied by an Editorial: Blood,110:3495-3496] Yang, XF, Yin, Y, Wang, H, Vascular inflammation and atherosclerosis are activated via receptors for PAMPs and suppressed by regulatory T cells. Drug Discovery Today 2008;5:125-142, PMID: 19578482 Zhang, D, Jiang, X, Pu, F, Yan Y, Song, J, Gupta, S, Schafer, AI, Durante, W, Kruger, W, Yang, XF and Wang, H., Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic CBS deficient mice. Circulation 2009; 120:1893-1902, PMID: 19858416 Chen NC, Yang F, Capecci LM, Gu ZY, Schafer AI, Durante W, Yang XF, Wang H, Regulation of homocysteine metabolism and methylation in human and mouse tissues, The FASEB Journal 2010;24(8):2804-17. PMID: 20305127 Cheng ZJ, Jiang XH, Kruger WD, Praticò D, Gupta S, Mallilankaran K, Muniswamy M, Schafer AI, Durante W, Yang XF, Wang H, Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta-synthase-deficient mice. Blood 2011;118:1998-2006 PMID:21653942 [Accompanied by an Editorial: Blood,118:1717-1719]